PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
Application:
- Identification of heterozygous carriers in breeding selection.
- Differential diagnosis of eye disorders.
Collie eye anomaly (CEA) is a developmental disorder of the eye characterised by hypoplasia (underdevelopment) of the choroid. In severe cases CEA leads to blindness. The disease occurs in...

Application:
- Identification of heterozygous carriers
The test examines the mutation in the RPGRIP1 gene, which is a risk factor for cone-rod dystrophy 4-progressive retinal atrophy (crd4/cord1-PRA) in longhaired miniature dachshunds.This is a complex disease in which other gene mutations also play an important role in disease progression.

Test indication: a) Identfication of carriers among offsping of a carrier x free mating. b) Differential diagnosis of clinical PRA cases.
crd-PRA is an early onset type of PRA described for wirehaired dachshunds. The defect occurs in the NPHP4 gene and has an autosomal-recessive mode of inheritance.

Application: - Carrier identification - Differential diagnosis in clinical PRA.
With this test we investigate if the dog carries a mutation in the SLC4A3-gene that was identified as the cause of GR_PRA1. PRA (Progressive Retinal Atrophy) is the name for a group of diseases of the eye. They are characterised by a progressive degeneration of the retina that eventually leads...

Application: - Carrier identification - Differential diagnosis in clinical PRA.
With this test we investigate if the dog carries a mutation in the TTC8-gene that was identified as the cause of GR_PRA2. PRA (Progressive Retinal Atrophy) is the name for a group of diseases of the eye. They are characterised by a progressive degeneration of the retina that eventually leads to...

PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
Application of the test:
- Differential diagnosis in clinical PRA
- Detection of mixed-breed, healthy carriers for breeding selection
The tested mutation is a hereditary cause for the onset of PRA, especially in Labrador Retrievers.
The inheritance is autosomal recessive; the hereditary disease occurs when both...

PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
*** = the test is carried out in a partner laboratory

Application:
- Identification of heterozygous carriers for breeding selection
- Differential diagnosis in case of visual impairment
The test examines whether the mutation (c.4176insC) in the ABCA4 gene that causes 'Stargardt Disease' (STGD) is present. The mode of inheritance is autosomal recessive, so that only animals in which both hereditary factors are defective develop...