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Musculature
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MIM-6 Var. (prev. “PSSM2”)
Order number: GCH208
  • Included DNA tests:
  • - P2
  • - P3
  • - P4
  • - Px
  • - P8
  • - K1
    • €249.90 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    Application: - Clarification of underlying causes in symptomatic horses - Predisposition assessment in the context of a pre-purchase examination - Mating planning. The MIM-6 variant test replaces the name 'PSSM2 test' to reflect the effects of the tested variants and their significance for exertional myopathies. The test still contains the 6 gene variants P2, P3, P4, P8, Px,...
    MIM-6 Var. (prev. “PSSM2”) EXPRESS
    Order number: GCH208e
  • Included DNA tests:
  • - P2
  • - P3
  • - P4
  • - Px
  • - P8
  • - K1
    • €327.25 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    You will receive the results of the MIM-6 Var.-Test within 5 working days from the time the sample is accepted in the laboratory. Please note the guidelines below when ordering: - Please do not order a separate sampling set , instead please follow our instructions for hair sample collection: Link . - Send the sample to: Generatio GmbH - Center for Animal Genetics |...
    MIM-6 Var. (prev. “PSSM2”) ISLANDIC
    Order number: GCH230
  • Included DNA tests:
  • - P3
  • - P8
  • - K1
    • €147.91 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    MIM-3 Variant (P3, P8, K1). This panel is available only to Icelandic horses. The panel tests the only three MIM ("PSSM2) variants known to occur in Icelandic Horses.
    Congenital Myotonia
    Order number: GSH109
    €53.90 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    Congenital Myotonia leads to impaired movement due to muscle rigidity. It is autosomal recessive and is found in New Forest ponies and other ponies with the stallion "Kantje's Ronaldo" in the pedigree.
    Glycogen Branching Enzyme Deficiency (GBED)
    Order number: GSH103
    €49.90 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    This test detects the c.102C>A mutation in GBE1 that causes Glycogen Branching Enzyme Deficiency in Quarter Horses and related breeds. The inheritance is autosomal recessive so only animals with two defective copies (gbed/gbed) will be affected
    Hyperkalemic Periodic Paralysis (HYPP)
    Order number: GSH107
    €53.90 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    This test detects the c.4248C>G mutation in the SCN4A gene which causes Hyperkalemic Periodic Paralysis in Quarter Horses and related breeds (Impressive-bred). The inheritance is incomplete autosomal dominant. Animals with one (n/HYPP) or two (HYPP/HYPP) copies of the mutation will be affected.
    Malignant Hyperthermia - HORSE
    Order number: GSH110
    €53.90 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    Malignant Hyperthermia is an autosomal dominant mutation where fever, muscle rigidity and respiratory distress and even death can be triggered by specific anaesthetics or other stress/exercise. It also worsens the symptoms of horses with PSSM1 and 2.
    MYH1 Myopathy / Immune-mediated Myositis (IMM)
    Order number: GSH124
    €53.90 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    MYH1 Myopathy is a hereditary disease with incomplete/semi-dominant inheritance, caused by a mutation (chr11:52993878T>C; E321G) in the MYH1 Myosin Heavy Chain 1 gene. This mutation is a major risk factor horse horses to develop Immune mediated myopathy (IMM) and non-exertional rhabdomyolysis. IMM affected animals can exhibit muscle extreme loss (especially in the hind...
    Polysaccharide Storage Myopathy 1 (PSSM1***)
    Order number: PSH128
  • *** Partner laboratory
    • €58.91 VAT incl.
    List price - personal prices are available after logging into ATC user account.
    PSSM1 is a form of exercise intolerance in which a disorder of the sugar metabolism of the muscles causes muscle damage.
    The test detects the mutation (c.926G>A) in the GYS1 gene which causes PSSM1. The inheritance is incomplete autosomal dominant. Horses with one or two copies of the genetic variant (n/P1 or P1/P1) are at risk to develop symptoms of PSSM1; those with two...