STGD - Stargardt Disease

Order number: GSD573
€46.41

VAT incl.

Application: - Identification of heterozygous carriers for breeding selection - Differential diagnosis in case of visual impairment The test examines whether the mutation (c.4176insC) in the ABCA4 gene that causes 'Stargardt Disease' (STGD) is present. The mode of inheritance is autosomal recessive, so that only animals in which both hereditary factors are defective develop the disease.... more
Product information "STGD - Stargardt Disease"
Application:
- Identification of heterozygous carriers for breeding selection
- Differential diagnosis in case of visual impairment
The test examines whether the mutation (c.4176insC) in the ABCA4 gene that causes 'Stargardt Disease' (STGD) is present. The mode of inheritance is autosomal recessive, so that only animals in which both hereditary factors are defective develop the disease. Affected animals show a progressive degeneration of the retina, which initially causes an impairment of visual acuity in the central visual field. As the disease progresses, both day and night vision deteriorate; complete blindness has not yet been described.
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Classification:
Type: DNA tests
Species: Dog
Class: Inherited diseases
Breeding clubs: Deutscher Retriever Club e.V., DRC. DNA-Programm Identität und Eigenschaften
Breed: Labrador Retriever, Mischling Hund
Group: Eyes
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Copper storage tox. Labrador type [p]
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A – Locus / Agouti - DOG
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CNM
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crd-PRA
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Furnishings
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Glykogen storage disease GSDIIIa
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Golden Retriever PRA 1
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Harlekin coat pattern
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Malignant Hyperthermia
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Merle coat pattern
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Narcolepsia (Dachshund)
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Osteogenesis Imperfecta (Dachshund)
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S – Locus (Piebald)
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Skeletal Dysplasia 2
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Von-Willebrand-Disease Type 1
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Golden Retriever muscular dystrophy
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Cystinurie Typ I-A
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prcd-PRA***
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HNPK
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Exercise Induced Collapse (EIC)***
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Ichtyosis (ICT-A)***
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Collie eye anomaly (CEA)***
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Degenerative Myelopathy (DM)***
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Hämophilie B [p]
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DNA profile Identity DOG (ISAG-22-Marker)
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DNA profile Identity DOG - *** class, extended...
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