DNA Tests
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A – Locus / Agouti - DOG
Order number: GSD209
€65.45 VAT incl.
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Application: Identification of hidden alleles in breeds that show A-locus dependent variation in coat colors. The four A-Locus alleles are expressed as a hierarchy: a(y) > a(w) > a(t) > a. A- locus predispositions only take effect if there is no „K(B)“-allele at the K-Locus and at least one „E“-allele at the E-Locus. Other loci (B-Locus, D-Locus) may also influence A-Locus...
ACAN-Dwarfism/Chondrodysplasia
Order number: GSH118
€77.90 VAT incl.
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ACAN-dwarfism is found in Shetland ponies and miniature horses, in which abnormal cartilage growth leading to skeletal problems and dwarfism. Four different disease-causing variants of the ACAN gene are known so far: d1, d2, d3* and d4. The inheritance is autosomal recessive.
Agouti (A locus) Horse
Order number: GSH200
€53.90 VAT incl.
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The Agouti gene (A) is involved with the production of both red (pheomelanin) and black (eumelanin) pigments. It regulates the relative amounts of each pigment produced in melanocytes (pigment-producing cells) in different regions of the horse’s body. A functional version (AA or Ae) results in a horse that has a base color of bay with black mane, tail, legs and ear tips. Two...
B – Locus (Coat color 'Brown' - DOG)
Order number: GSD212
€65.45 VAT incl.
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Application: Testing coat color 'brown' identifies animals that carry „b“-alleles. The brown coat color can develop if both genes are 'affected' (b/b) and an „E“-Allel at the E-locus is present. Effective Ay and Aw alleles at the A-locus may hide a b/b situation. 3 loci are analysed.
CDDY & IVDD
Order number: GSD564
€53.90 VAT incl.
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The test identifies the presence of the FGF4 retrogene insertion on chromosome 12. This mutation is one cause of shortened legs (CDDY, disproportional dwarfism) in dogs. It is also a risk factor for the occurrence of Hansen type 1 disc herniation (IVDD type 1). Leg length will differ depending on if the dog has one or two copies of the mutation as the mutation is incomplete...
CDN - Colour Dilution Neuropathy, Griscelli...
Order number: GSD144
€53.90 VAT incl.
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The hereditary disease, whose causative mutation in the MYO5A gene is detected with the test, was initially called Griscelli type 1 analogue syndrome because of the analogy in humans. In dogs, the term 'Colour Dilution Neuropathy' (CDN) has become common as well.
The mode of inheritance is autosomal recessive. If homozygous, living but non-viable puppies are born....
The mode of inheritance is autosomal recessive. If homozygous, living but non-viable puppies are born....
CDPA - Chrondrodysplasia
Order number: GSD155
€53.90 VAT incl.
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The test examines whether the FGF4L1 retrogen insertion is present in the chromosome 18 (CFA18) of the investigated dog. This mutation is described as a cause of chondrodysplasia (CDPA) or short-legged phenotype in dogs. The inheritance is autosomal dominant.
Centronuclear Myopathy (CNM)
Order number: GSD176
€53.90 VAT incl.
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Application: a) Carrier identification in offspring after mating of a 'CNM-carrier' with a 'CNM-free' animal, b) Differential diagnosis in cases of clinical muscle insufficiency. Centronuclear Myopathy (CNM), also described as HMLR, or Hereditary Myopathy of Labrador Retrievers, has an autosomal recessive expression. Affected animals show insufficient muscle function...
Cerebellar Abiotrophy (CA)
Order number: GSH102
€53.90 VAT incl.
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Cerebellar Abiotrophy is an autosomal recessive disease where affected animals develop ataxia due to the progressive death of brain cells responsible for movement. It is found in Arabians and related breeds.
Cerebellar hypoplasia (Dandy Walker Like...
Order number: GSD362
€53.90 VAT incl.
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Application: - Heterozygous carrier identification - Differential diagnosis in cases of locomotion and coordination problems
DWLM is a hypoplasia of the cerebellum that results in ataxia with varying severity from staggering gait to episodic falling. First symptoms appear when the dog starts to walk. It is in an autosomal recessively inherited disease, only dogs with two...
DWLM is a hypoplasia of the cerebellum that results in ataxia with varying severity from staggering gait to episodic falling. First symptoms appear when the dog starts to walk. It is in an autosomal recessively inherited disease, only dogs with two...
Champagne
Order number: GSH201
€53.90 VAT incl.
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Horses with one or two copies of the Champagne mutation will have diluted coat color, including mane and tail. Classic Champagne (black base color), Gold Champagne (chestnut base color), Amber Champagne (bay base color) are possible.
Collie eye anomaly (CEA)*** *** Partner laboratory
Order number: PSD570
€82.11 VAT incl.
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PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
Application:
- Identification of heterozygous carriers in breeding selection.
- Differential diagnosis of eye disorders.
Collie eye anomaly (CEA) is a developmental disorder of the eye characterised by hypoplasia (underdevelopment) of the choroid. In severe cases CEA leads to blindness. The disease occurs in...
Application:
- Identification of heterozygous carriers in breeding selection.
- Differential diagnosis of eye disorders.
Collie eye anomaly (CEA) is a developmental disorder of the eye characterised by hypoplasia (underdevelopment) of the choroid. In severe cases CEA leads to blindness. The disease occurs in...