Application:
- Differential diagnosis in case of clinical symptoms
- Detection of carriers that appear healthy
The CysII-B test identifies the mutation that causes Cystinuria in Miniature Pinschers. The mutation effect is autosomal dominant, but clinical symptoms can be very mild with dogs appearing healthy.

Application:
- Identification of clinically normal, heterozygous carriers. - Differential diagnosis in cases of manifest cystinuria.
The mutation investigated is responsible for cystinuria type I-A (CysI-A) in Newfoundland and Landseer dogs. The mode of inheritance is autosomal recessive.

Application of the test:
(a) identification of carrier animals from a mating of carrier x free animal. b) Differential diagnosis in urinary stones and inflammation of the urogenital tract.
It is investigated whether the dog carries the mutation in the gene SLC2A9, which has been described as a cause of hyperuricosuria. Hyperuricosuria is the presence of excessive amounts of...