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A – Locus / Agouti - DOG
Order number: GSD209
€65.45 VAT incl.
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Application: Identification of hidden alleles in breeds that show A-locus dependent variation in coat colors. The four A-Locus alleles are expressed as a hierarchy: a(y) > a(w) > a(t) > a. A- locus predispositions only take effect if there is no „K(B)“-allele at the K-Locus and at least one „E“-allele at the E-Locus. Other loci (B-Locus, D-Locus) may also influence A-Locus...
B – Locus (Coat color 'Brown' - DOG)
Order number: GSD212
€65.45 VAT incl.
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Application: Testing coat color 'brown' identifies animals that carry „b“-alleles. The brown coat color can develop if both genes are 'affected' (b/b) and an „E“-Allel at the E-locus is present. Effective Ay and Aw alleles at the A-locus may hide a b/b situation. 3 loci are analysed.
CDDY & IVDD
Order number: GSD564
€53.90 VAT incl.
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The test identifies the presence of the FGF4 retrogene insertion on chromosome 12. This mutation is one cause of shortened legs (CDDY, disproportional dwarfism) in dogs. It is also a risk factor for the occurrence of Hansen type 1 disc herniation (IVDD type 1). Leg length will differ depending on if the dog has one or two copies of the mutation as the mutation is incomplete...
Centronuclear Myopathy (CNM)
Order number: GSD176
€53.90 VAT incl.
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Application: a) Carrier identification in offspring after mating of a 'CNM-carrier' with a 'CNM-free' animal, b) Differential diagnosis in cases of clinical muscle insufficiency. Centronuclear Myopathy (CNM), also described as HMLR, or Hereditary Myopathy of Labrador Retrievers, has an autosomal recessive expression. Affected animals show insufficient muscle function...
Cerebellar hypoplasia (Dandy Walker Like...
Order number: GSD362
€53.90 VAT incl.
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Application: - Heterozygous carrier identification - Differential diagnosis in cases of locomotion and coordination problems
DWLM is a hypoplasia of the cerebellum that results in ataxia with varying severity from staggering gait to episodic falling. First symptoms appear when the dog starts to walk. It is in an autosomal recessively inherited disease, only dogs with two...
DWLM is a hypoplasia of the cerebellum that results in ataxia with varying severity from staggering gait to episodic falling. First symptoms appear when the dog starts to walk. It is in an autosomal recessively inherited disease, only dogs with two...
Collie eye anomaly (CEA)*** *** Partner laboratory
Order number: PSD570
€82.11 VAT incl.
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PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
Application:
- Identification of heterozygous carriers in breeding selection.
- Differential diagnosis of eye disorders.
Collie eye anomaly (CEA) is a developmental disorder of the eye characterised by hypoplasia (underdevelopment) of the choroid. In severe cases CEA leads to blindness. The disease occurs in...
Application:
- Identification of heterozygous carriers in breeding selection.
- Differential diagnosis of eye disorders.
Collie eye anomaly (CEA) is a developmental disorder of the eye characterised by hypoplasia (underdevelopment) of the choroid. In severe cases CEA leads to blindness. The disease occurs in...
Cone-rod dystrophy 4 - Progressive Retinal...
Order number: GSD361
€53.90 VAT incl.
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Application:
- Identification of heterozygous carriers
The test examines the mutation in the RPGRIP1 gene, which is a risk factor for cone-rod dystrophy 4-progressive retinal atrophy (crd4/cord1-PRA) in longhaired miniature dachshunds.This is a complex disease in which other gene mutations also play an important role in disease progression.
- Identification of heterozygous carriers
The test examines the mutation in the RPGRIP1 gene, which is a risk factor for cone-rod dystrophy 4-progressive retinal atrophy (crd4/cord1-PRA) in longhaired miniature dachshunds.This is a complex disease in which other gene mutations also play an important role in disease progression.
crd-PRA
Order number: GSD307
€53.90 VAT incl.
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Test indication: a) Identfication of carriers among offsping of a carrier x free mating. b) Differential diagnosis of clinical PRA cases.
crd-PRA is an early onset type of PRA described for wirehaired dachshunds. The defect occurs in the NPHP4 gene and has an autosomal-recessive mode of inheritance.
crd-PRA is an early onset type of PRA described for wirehaired dachshunds. The defect occurs in the NPHP4 gene and has an autosomal-recessive mode of inheritance.
Curly Coat
Order number: GSD505
€53.90 VAT incl.
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Application: Identification of carriers for straight coat.
In most dog breeds curly hair is caused by a mutation in the KRT71 gene. A single defect is sufficient representing a dominant autosomal mode of inheritance. This mode allows for carriers with hidden non-curly alleles. Mating of a carrier dam with a carrier sire will result in 25% non-curly offspring. Long hair...
In most dog breeds curly hair is caused by a mutation in the KRT71 gene. A single defect is sufficient representing a dominant autosomal mode of inheritance. This mode allows for carriers with hidden non-curly alleles. Mating of a carrier dam with a carrier sire will result in 25% non-curly offspring. Long hair...
Cystinuria II-B
Order number: GSD166
€53.90 VAT incl.
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Application:
- Differential diagnosis in case of clinical symptoms
- Detection of carriers that appear healthy
The CysII-B test identifies the mutation that causes Cystinuria in Miniature Pinschers. The mutation effect is autosomal dominant, but clinical symptoms can be very mild with dogs appearing healthy.
- Differential diagnosis in case of clinical symptoms
- Detection of carriers that appear healthy
The CysII-B test identifies the mutation that causes Cystinuria in Miniature Pinschers. The mutation effect is autosomal dominant, but clinical symptoms can be very mild with dogs appearing healthy.
Cystinuria-A (Newfoundland)
Order number: GSD164
€53.90 VAT incl.
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Application:
- Identification of clinically normal, heterozygous carriers. - Differential diagnosis in cases of manifest cystinuria.
The mutation investigated is responsible for cystinuria type I-A (CysI-A) in Newfoundland and Landseer dogs. The mode of inheritance is autosomal recessive.
- Identification of clinically normal, heterozygous carriers. - Differential diagnosis in cases of manifest cystinuria.
The mutation investigated is responsible for cystinuria type I-A (CysI-A) in Newfoundland and Landseer dogs. The mode of inheritance is autosomal recessive.
D – Locus (Dilution)
Order number: GSD508
€53.90 VAT incl.
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Application: - Carrier identification. Coat color dilution is autosomal-recessive. Dilution manifests if the mutation is homozygous (d/d). A dog with two variant copies of the MLPH gene will have a blue, charcoal, Isabella (lilac) or fawn coat color depending on the other coat color genes present in the individual. In some breeds dilute coat color can be associated with...