Combo package for the two base colors of horse coat coloring (Agouti, Extension).

MIM - 6 Variant is the new name for the test that was previously offered as the PSSM2 test. The adaptation reflects the current findings in the field of exertional myopathies. The tests comprises the 6 gene variants (P2, P3, P4, P8, Px,K1) that are important genetic predispositions for the development of MIM (Muscle Integrity Myopathy), a specific form of exertional...

You will receive the results of the MIM-6 Var.-Test within 3 working days from the time the sample is accepted in the laboratory. Please note the following information when ordering: - Please do not order a separate sample collection set, instead please follow our instructions for hair sample collection: ( link ). - Send the sample to: Generatio GmbH - Center for Animal...

The Agouti gene (A) is involved with the production of both red (pheomelanin) and black (eumelanin) pigments. It regulates the relative amounts of each pigment produced in melanocytes (pigment-producing cells) in different regions of the horse’s body. A functional version (AA or Ae) results in a horse that has a base color of bay with black mane, tail, legs and ear tips. Two...

Cerebellar Abiotrophy is an autosomal recessive disease where affected animals develop ataxia due to the progressive death of brain cells responsible for movement. It is found in Arabians and related breeds.

Dun is the original coat color of all horses (wild-type). Over time, two mutations (nd1 and nd2) caused the now wide-spread undiluted phenotypes most modern horses display. Horses with one or two copies of this variant (D/D, D/nd1, D/nd2) are Dun and show the diluted coat color and the primitive markings (zebra stripes, dorsal stripe) on their legs and back. A dun horse must...

Horses with two copies of the MC1R variant (ee) are chestnut (red, sorrel) in color. Horses with only one copy of this variant (Ee) are bay or black-based (depending upon their variants at the Agouti locus), but carry chestnut. A horse that does not carry the variant (EE) cannot have a chestnut foal, even if bred to a chestnut horse.

The test detects the mutation in the STX17 gene (a 4.6 kb intronic duplication) which is causative for the Grey coat color. It is also a risk factor for melanoma. The inheritance is autosomal dominant. Horses with one or two copies of the genetic variant (n/G or G/G) will grey with time. This test detects if a horse has one or two copies of the Grey mutation.

Malignant Hyperthermia is an autosomal dominant mutation where fever, muscle rigidity and respiratory distress and even death can be triggered by specific anaesthetics or other stress/exercise. It also worsens the symptoms of horses with PSSM1 and 2.

SCID is caused by the improper development of cells of the immune system (T- and B cells) and causes severe, non-specific infections which are usually fatal.

Splashed White 1 (SW1) is a variant found in many different breeds. It is autosomal semi-dominant, so horses with two copies (SW1/SW1) have a more extreme phenotype than those with only one copy (n/SW1). Horses with one copy usually have a wide blaze, often wider on the lower part of the face. The face-white may be associated with blue eyes, white stockings and small white...

The test determines if the MITF mutation (EquCab3: Chr16:21567245_21567249delGTGTCT) which causes the Splashed White 3 (SW3) phenotype is present. The inheritance is autosomal semi-dominant. SW3 originated in the Quarter Horse "TD Kid".