The package bundles tests on coat colors (B-Locus, D-Locus, E-Locus), which may be important for various retriever breeds.

Application: Identification of hidden alleles in breeds that show A-locus dependent variation in coat colors. The four A-Locus alleles are expressed as a hierarchy: a(y) > a(w) > a(t) > a. A- locus predispositions only take effect if there is no „K(B)“-allele at the K-Locus and at least one „E“-allele at the E-Locus. Other loci (B-Locus, D-Locus) may also influence A-Locus...

Application: Testing coat color 'brown' identifies animals that carry „b“-alleles. The brown coat color can develop if both genes are 'affected' (b/b) and an „E“-Allel at the E-locus is present. Effective Ay and Aw alleles at the A-locus may hide a b/b situation. 3 loci are analysed.

The test identifies the presence of the FGF4 retrogene insertion on chromosome 12. This mutation is one cause of shortened legs (CDDY, disproportional dwarfism) in dogs. It is also a risk factor for the occurrence of Hansen type 1 disc herniation (IVDD type 1). Leg length will differ depending on if the dog has one or two copies of the mutation as the mutation is incomplete...

PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
Application:
- Identification of heterozygous carriers in breeding selection.
- Differential diagnosis of eye disorders.
Collie eye anomaly (CEA) is a developmental disorder of the eye characterised by hypoplasia (underdevelopment) of the choroid. In severe cases CEA leads to blindness. The disease occurs in...

Application: - Carrier identification. Coat color dilution is autosomal-recessive. Dilution manifests if the mutation is homozygous (d/d). A dog with two variant copies of the MLPH gene will have a blue, charcoal, Isabella (lilac) or fawn coat color depending on the other coat color genes present in the individual. In some breeds dilute coat color can be associated with...

This DNA-profile identity contains additional markers for increased reliability in parentage testing and especially for determining genetic diversity.
IT IS NOT REQUIRED IN THIS FORM BY ANY BREEDING COMPANY - the basic ISAG marker set is sufficient (article GDI100)

With this ID-profile a requirement for breeding approval at various breeding clubs in Germany but also abroad is fulfilled (see DNA-programs, e.g. DTK, DNK, DRC, VND or KZG). The set is internationally distributed and consists of the 22 recommended markers.
The result is issued as an ATC certificate identity with electronic signature and can be securely communicated over the...

Application: - identification of heterozygous carriers
Genetic testing of the MC1R mutation c.916 C>T will determine whether a dog is a carrier of the predisposition for coat color 'yellow' / 'red'. The trait is inherited in an autosomal recessive manner, two copies of the e allele (genotype e/e) are required to have the characteristic yellow/red coat color.

Application: Carrier identification. Genetic testing of this MC1R variant will determine whether a dog is a carrier of melanistic mask alleles. The trait is inherited in an autosomal dominant manner. A single copy of the Em allele (genotype Em/E) is sufficient to have the characteristic mask.

Application of the test:
(a) identification of carrier animals from a mating of carrier x free animal. b) Differential diagnosis in urinary stones and inflammation of the urogenital tract.
It is investigated whether the dog carries the mutation in the gene SLC2A9, which has been described as a cause of hyperuricosuria. Hyperuricosuria is the presence of excessive amounts of...

Application:
- Identification of predisposition K(B). This test examines whether the dog carries the dominant K(B) allele. If this is present, the animal has a solid black coat in the pigmented areas and the effect of the A-locus is not observed. If the animal has the genotype 'b/b' at the B-locus, the coat colour would not be black, but brown. The effect of the genotype at...