Combo package for the two base colors of horse coat coloring (Agouti, Extension).

Combo package covering 3 common coat color dilution factors (Cream, Champagne, Silver).

Application: - Clarification of underlying causes in symptomatic horses - Predisposition assessment in the context of a pre-purchase examination - Mating planning. The MIM-6 variant test replaces the name 'PSSM2 test' to reflect the effects of the tested variants and their significance for exertional myopathies. The test still contains the 6 gene variants P2, P3, P4, P8, Px,...

You will receive the results of the MIM-6 Var.-Test within 5 working days from the time the sample is accepted in the laboratory. Please note the guidelines below when ordering: - Please do not order a separate sampling set , instead please follow our instructions for hair sample collection: Link . - Send the sample to: Generatio GmbH - Center for Animal Genetics |...

The Agouti gene (A) is involved with the production of both red (pheomelanin) and black (eumelanin) pigments. It regulates the relative amounts of each pigment produced in melanocytes (pigment-producing cells) in different regions of the horse’s body. A functional version (AA or Ae) results in a horse that has a base color of bay with black mane, tail, legs and ear tips. Two...

Horses with one or two copies of the Champagne mutation will have diluted coat color, including mane and tail. Classic Champagne (black base color), Gold Champagne (chestnut base color), Amber Champagne (bay base color) are possible.

The Cream mutation dilutes the red pigment (phaeomelanin) in the hair. It is incomplete dominant: one copy of the cream dilution (n/Cr) results in Palomino and Buckskin coat colors; Smoky Black (black carrying cream) horses look the same as normal black. With two copies of the Cream variant (Cr/Cr), the dilution effect is complete, giving the Cremello, Perlino, and Smoky...

Dun is the original coat color of all horses (wild-type). Over time, two mutations (nd1 and nd2) caused the now wide-spread undiluted phenotypes most modern horses display. Horses with one or two copies of this variant (D/D, D/nd1, D/nd2) are Dun and show the diluted coat color and the primitive markings (zebra stripes, dorsal stripe) on their legs and back. A dun horse must...

Horses with two copies of the MC1R variant (ee) are chestnut (red, sorrel) in color. Horses with only one copy of this variant (Ee) are bay or black-based (depending upon their variants at the Agouti locus), but carry chestnut. A horse that does not carry the variant (EE) cannot have a chestnut foal, even if bred to a chestnut horse.

The test detects the mutation in the STX17 gene (a 4.6 kb intronic duplication) which is causative for the Grey coat color. It is also a risk factor for melanoma. The inheritance is autosomal dominant. Horses with one or two copies of the genetic variant (n/G or G/G) will grey with time. This test detects if a horse has one or two copies of the Grey mutation.

Malignant Hyperthermia is an autosomal dominant mutation where fever, muscle rigidity and respiratory distress and even death can be triggered by specific anaesthetics or other stress/exercise. It also worsens the symptoms of horses with PSSM1 and 2.

The KIT Noriker roan allele has been found in Noriker, Lipizzan, Quarter Horse, Murgese and some draft breeds. It is not the classical roan mutation found in most roan quarter horses, but it has not yet been tested in a wide variety of breeds.