Combo package for the two base colors of horse coat coloring (Agouti, Extension).

Application:
- Clarification of underlying causes in horses symptomatic for Exertional Myopathy
- Pre-purchase examination: assessment of the risk of developing Exertional Myopathy type MIM due to genetic predisposition.
- Mating planning.
The test contains the 6 gene variants P2, P3, P4, P8, Px, K1, which are important genetic predispositions for the development of MIM =...

The Agouti gene (A) is involved with the production of both red (pheomelanin) and black (eumelanin) pigments. It regulates the relative amounts of each pigment produced in melanocytes (pigment-producing cells) in different regions of the horse’s body. A functional version (AA or Ae) results in a horse that has a base color of bay with black mane, tail, legs and ear tips. Two...

The Cream mutation dilutes the red pigment (phaeomelanin) in the hair. It is incomplete dominant: one copy of the cream dilution (n/Cr) results in Palomino and Buckskin coat colors; Smoky Black (black carrying cream) horses look the same as normal black. With two copies of the Cream variant (Cr/Cr), the dilution effect is complete, giving the Cremello, Perlino, and Smoky...

In the course of this examination, Generatio establishes the SNP markers, which, as DNA fingerprints, ensure the identity of a horse and, when compared in parentage assessments, show whether a parentage statement is correct. As a result, you will receive a DNA identity card in PDF format for each animal. To use SNP ID profiles in parentage assessments, all animals involved...

Horses with two copies of the MC1R variant (ee) are chestnut (red, sorrel) in color. Horses with only one copy of this variant (Ee) are bay or black-based (depending upon their variants at the Agouti locus), but carry chestnut. A horse that does not carry the variant (EE) cannot have a chestnut foal, even if bred to a chestnut horse.

The KIT Noriker roan allele has been found in Noriker, Lipizzan, Quarter Horse, Murgese and some draft breeds. It is not the classical roan mutation found in most roan quarter horses, but it has not yet been tested in a wide variety of breeds.

Height in animals depends on multiple factors including genes and the environment. One genetic variant (a single basepair change in the LCORL-regulatory region) has a strong influence on height in warmblood horses. This test enables breeders to predict a horse’s adult height before they are fully grown (accuracy: 70% ; +/- 5 cm) and to plan breedings to select for taller or...

Application:
- Identification of carriers in breeding selection
- Differential diagnosis in clinical cases of Exertional Myopathy.
PSSM1 is a form of Exertional Myopathy in which a disorder of the sugar metabolism of the muscles causes muscle damage.
The test detects the mutation (c.926G>A) in the GYS1 gene which causes PSSM1. The inheritance is incomplete autosomal...

Silver results in the decreased storage of the black pigment “eumelanin” in hair, so that horses with black and bay base colors will show a dilution. Horses with a Chestnut base color may be carriers for the Silver mutation but do not develop the diluted coat color themselves. Horses with only one copy of the variant (n/Z) will show the same phenotype as horses with two...

Splashed White 1 (SW1) is a variant found in many different breeds. It is autosomal semi-dominant, so horses with two copies (SW1/SW1) have a more extreme phenotype than those with only one copy (n/SW1). Horses with one copy usually have a wide blaze, often wider on the lower part of the face. The face-white may be associated with blue eyes, white stockings and small white...

SCC is a malignant tissue formation (tumor) that develops from the superficial layers of the skin and mucous membranes.