Juvenile Myoclonic Epilepsy

Application:
- Identification of heterozygous carriers
- Differential diagnosis in case of epileptic seizures
The test examines whether the dog carries the mutation c564_567delAGAC in the gene DIRAS1. According to current scientific knowledge, this is the cause of generalised myoclonic epilepsy in the Rhodesian Ridgeback. The mode of inheritance is monogenic autosomal recessive, i.e. the animals only become ill if both gene copies are defective. The first symptoms appear between 6 weeks and 18 months of age.