The bundle comprises a selection of tests on coat colors and coat characteristics that can play a role in the breeding selection of dachshunds of all varieties. (Merle, Haarlänge, Furnishing)

The test detects the mutation (c.643_644dup) in the EFNB3 gene that causes Congenital Mirror Movement Disorder 1 (CMM1). The inheritance is autosomal recessive, meaning that only animals carrying two copies of the mutated gene will be affected. Affected dogs can exhibit varying degrees of limb paralysis and a characteristic gait characterized by synchronous movements of both...

This SNP marker-based DNA profile identity has the same objective as the previously used STR-based ID profiles: - Ensuring identity,
- proof of origin - Basis for parentage assessments
At Generatio, the SNP ID profiles are based on a chip analysis; you will receive the result as a PDF as well as for downloading in the online animal record
PLEASE NOTE: 1: This Test is not...

This DNA-profile identity contains additional markers for increased reliability in parentage testing and especially for determining genetic diversity.
IT IS NOT REQUIRED IN THIS FORM BY ANY BREEDING COMPANY - the basic ISAG marker set is sufficient (article GDI100)
Please note: This DNA profile is not a breed determination.

With this ID-profile a requirement for breeding approval at various breeding clubs in Germany but also abroad is fulfilled (see DNA-programs, e.g. DTK, DNK, DRC, VND or KZG). The set is internationally distributed and consists of the 22 recommended markers.
The result is issued as an ATC certificate identity with electronic signature and can be securely communicated over the...

Application: - Identification of heterozygous carriers.
'Furnishings' are the long eyebrows and whiskers of wire-haired dogs. The predisposition is autosomal-dominant, so that only by testing can it be determined whether a phenotypically wire-haired animal is homozygous or heterozygous for 'Furnishings' and the wire-haired coat texture. Knowing the predisposition to...

Application.:
- Identification of carriers for long hair in short-haired dogs. - Proof of long-hair predisposition in cases of unclear phenotype.
Long hair is inherited in an autosomal recessive fashion, meaning that two copies (status L/L) of the long hair variant are required to produce long hair. Dogs with one copy (K/L) or no copies (K/K) will have short hair.

Application: - Identification of carriers of the MDR1 (ABCB1) variant prior to medication use - Breeding planning to prevent the transmission of the mutation In dogs with a homozygous ABCB1/MDR1 gene defect, there is an increased uptake of certain drugs into the central nervous system. This results in severe poisoning at normal dosage. Affected drugs include ivermectin,...

Application: - Identification of the effective and cryptic “Merle” variant. Merle” is a colour variation that occurs due to a mutation in the PMEL17/SILV gene. A prerequisite is that an “E” gene is present at the E locus. The variation is variable in extent and only develops its typical effect above a certain threshold value. Shorter variants do not appear and are considered...

The test determines the genome-based values for individual inbreeding and diversity values. Applications: - Clarification of an individual's inbreeding status in cases of unspecified general health issues. - Development of a genome-based mating planning scheme for the preservation or improvement of genetic diversity in a breeding population. Generatio determines all 3...

The combination provides the DNA profile 'Identity' of the ISAG2020 marker set (SNP markers) supplemented by an evaluation of the individual parameters for 'Inbreeding & Fitness' (genomic inbreeding coefficient, g-IK | extent of heterozygosity, HE value | ROH profile = size and position of the inbred regions on the chromosomes)
The analyses are based on SNP array analysis...