Golden Retriever muscular dystrophy

Order number: GSD363
€48.79

VAT incl.

Application: - Determination of the predisposition status for mating planning - Differential diagnosis of muscle weakness, muscle wasting The DMD:c.531-2A>G mutation in the DMD gene of the X chromosome of dogs is the causative factor for GRMD (X-linked Golden Retriever Muscular Dystrophy). The test investigates whether the mutation is present. The mode of inheritance is X-linked recessive. GRMD... more
Product information "Golden Retriever muscular dystrophy"
Application:
- Determination of the predisposition status for mating planning
- Differential diagnosis of muscle weakness, muscle wasting
The DMD:c.531-2A>G mutation in the DMD gene of the X chromosome of dogs is the causative factor for GRMD (X-linked Golden Retriever Muscular Dystrophy). The test investigates whether the mutation is present. The mode of inheritance is X-linked recessive. GRMD breaks out when both genes in the females and the single gene in the males have the mutation. Breeding with carrier dams should be avoided as 50% of the male offspring will have a mutated DMD gene and will develop the disease.
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Classification:
Type: DNA tests
Species: Dog
Class: Inherited diseases
Breeding clubs: Deutscher Retriever Club e.V., DRC. DNA-Programm Identität und Eigenschaften
Breed: Golden Retriever, Mischling Hund
Group: Musculoskeletal system
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Glykogen storage disease GSDIIIa
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Golden Retriever PRA 1
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