Glykogen storage disease GSDIIIa

Application:
- Carrier identification
- Differential diagnosis.
With this test we investigate if the dog carries a mutation in the AGL-gene that was described as the cause of Glycogen Storage Disease (GSD) type IIIa in Curly Coated Retrievers.
In their early years symptoms often cannot be recognized. But later they progress and affected dogs are lethargic, show exercise intolerance and episodic hypoglycaemia with collapse/unresponsiveness.
The disease is inherited in an autosomal recessive manner, only dogs with two mutated alleles are affected.