The package bundles tests on coat colors (B-Locus, D-Locus, E-Locus), which may be important for various retriever breeds.

Application: Identification of hidden alleles in breeds that show A-locus dependent variation in coat colors. The four A-Locus alleles are expressed as a hierarchy: a(y) > a(w) > a(t) > a. A- locus predispositions only take effect if there is no „K(B)“-allele at the K-Locus and at least one „E“-allele at the E-Locus. Other loci (B-Locus, D-Locus) may also influence A-Locus...

Application: Testing coat color 'brown' identifies animals that carry „b“-alleles. The brown coat color can develop if both genes are 'affected' (b/b) and an „E“-Allel at the E-locus is present. Effective Ay and Aw alleles at the A-locus may hide a b/b situation. 3 loci are analysed.

This test investigates if the dog carries the mutation in the BEST1 gene that has been described as cause for the disease Canine Multifocal Retinopathy 1 (cmr1) in mastiff-related breeds.The disease is inherited as an autosomal recessive characteristic and only occurs if the dog carries two mutated alleles.

Cone-Rod Dystrophy 1, also known as crd1, is a disease in which the cone and rod cells in the retina degenerate, leading to blindness. Clinical signs can be seen as early as 11 weeks of age, and full blindness results in early adulthood.

Application: Identification of carriers for straight coat.
In most dog breeds curly hair is caused by a mutation in the KRT71 gene. A single defect is sufficient representing a dominant autosomal mode of inheritance. This mode allows for carriers with hidden non-curly alleles. Mating of a carrier dam with a carrier sire will result in 25% non-curly offspring. Long hair...

Application: - Carrier identification. Coat color dilution is autosomal-recessive. Dilution manifests if the mutation is homozygous (d/d). A dog with two variant copies of the MLPH gene will have a blue, charcoal, Isabella (lilac) or fawn coat color depending on the other coat color genes present in the individual. In some breeds dilute coat color can be associated with...

This DNA-profile identity contains additional markers for increased reliability in parentage testing and especially for determining genetic diversity.
IT IS NOT REQUIRED IN THIS FORM BY ANY BREEDING COMPANY - the basic ISAG marker set is sufficient (article GDI100)

With this ID-profile a requirement for breeding approval at various breeding clubs in Germany but also abroad is fulfilled (see DNA-programs, e.g. DTK, DNK, DRC, VND or KZG). The set is internationally distributed and consists of the 22 recommended markers.
The result is issued as an ATC certificate identity with electronic signature and can be securely communicated over the...

Application: - identification of heterozygous carriers
Genetic testing of the MC1R mutation c.916 C>T will determine whether a dog is a carrier of the predisposition for coat color 'yellow' / 'red'. The trait is inherited in an autosomal recessive manner, two copies of the e allele (genotype e/e) are required to have the characteristic yellow/red coat color.

Application: Carrier identification. Genetic testing of this MC1R variant will determine whether a dog is a carrier of melanistic mask alleles. The trait is inherited in an autosomal dominant manner. A single copy of the Em allele (genotype Em/E) is sufficient to have the characteristic mask.

Application of the test:
(a) identification of carrier animals from a mating of carrier x free animal. b) Differential diagnosis in urinary stones and inflammation of the urogenital tract.
It is investigated whether the dog carries the mutation in the gene SLC2A9, which has been described as a cause of hyperuricosuria. Hyperuricosuria is the presence of excessive amounts of...