Application: Identification of hidden alleles in breeds that show A-locus dependent variation in coat colors. The four A-Locus alleles are expressed as a hierarchy: a(y) > a(w) > a(t) > a. A- locus predispositions only take effect if there is no „K(B)“-allele at the K-Locus and at least one „E“-allele at the E-Locus. Other loci (B-Locus, D-Locus) may also influence A-Locus...

Application: Testing coat color 'brown' identifies animals that carry „b“-alleles. The brown coat color can develop if both genes are 'affected' (b/b) and an „E“-Allel at the E-locus is present. Effective Ay and Aw alleles at the A-locus may hide a b/b situation. 3 loci are analysed.

The test detects the mutation (c.643_644dup) in the EFNB3 gene that causes Congenital Mirror Movement Disorder 1 (CMM1). The inheritance is autosomal recessive, meaning that only animals carrying two copies of the mutated gene will be affected. Affected dogs can exhibit varying degrees of limb paralysis and a characteristic gait characterized by synchronous movements of both...

Application: - Carrier identification. Coat color dilution is autosomal-recessive. Dilution manifests if the mutation is homozygous (d/d). A dog with two variant copies of the MLPH gene will have a blue, charcoal, Isabella (lilac) or fawn coat color depending on the other coat color genes present in the individual. In some breeds dilute coat color can be associated with...

This SNP marker-based DNA profile identity has the same objective as the previously used STR-based ID profiles: - Ensuring identity,
- proof of origin - Basis for parentage assessments
At Generatio, the SNP ID profiles are based on a chip analysis; you will receive the result as a PDF as well as for downloading in the online animal record
PLEASE NOTE: 1: This Test is not...

This DNA-profile identity contains additional markers for increased reliability in parentage testing and especially for determining genetic diversity.
IT IS NOT REQUIRED IN THIS FORM BY ANY BREEDING COMPANY - the basic ISAG marker set is sufficient (article GDI100)
Please note: This DNA profile is not a breed determination.

With this ID-profile a requirement for breeding approval at various breeding clubs in Germany but also abroad is fulfilled (see DNA-programs, e.g. DTK, DNK, DRC, VND or KZG). The set is internationally distributed and consists of the 22 recommended markers.
The result is issued as an ATC certificate identity with electronic signature and can be securely communicated over the...

Application: - identification of heterozygous carriers
Genetic testing of the MC1R mutation c.916 C>T will determine whether a dog is a carrier of the predisposition for coat color 'yellow' / 'red'. The trait is inherited in an autosomal recessive manner, two copies of the e allele (genotype e/e) are required to have the characteristic yellow/red coat color.

Application: Carrier identification. Genetic testing of this MC1R variant will determine whether a dog is a carrier of melanistic mask alleles. The trait is inherited in an autosomal dominant manner. A single copy of the Em allele (genotype Em/E) is sufficient to have the characteristic mask.

Application.:
- Identification of carriers for long hair in short-haired dogs. - Proof of long-hair predisposition in cases of unclear phenotype.
Long hair is inherited in an autosomal recessive fashion, meaning that two copies (status L/L) of the long hair variant are required to produce long hair. Dogs with one copy (K/L) or no copies (K/K) will have short hair.

Application: - Identification of carriers of the MDR1 (ABCB1) variant prior to medication use - Breeding planning to prevent the transmission of the mutation In dogs with a homozygous ABCB1/MDR1 gene defect, there is an increased uptake of certain drugs into the central nervous system. This results in severe poisoning at normal dosage. Affected drugs include ivermectin,...

Application: - Determination of the predisposition status for breeding planning. - Diagnosis in case of partial white colouring.
This test is used to determine whether the dog carries the hereditary disposition for the piebald pattern. According to Schmutz et al, the SINE insertion tested can be a marker for the piebald allele with an accuracy of at least 95% in those dog...