The package bundles tests on coat colors (B-Locus, D-Locus, E-Locus), which may be important for various retriever breeds.

Application: Testing coat color 'brown' identifies animals that carry „b“-alleles. The brown coat color can develop if both genes are 'affected' (b/b) and an „E“-Allel at the E-locus is present. Effective Ay and Aw alleles at the A-locus may hide a b/b situation. 3 loci are analysed.

Application: - Carrier identification. Coat color dilution is autosomal-recessive. Dilution manifests if the mutation is homozygous (d/d). A dog with two variant copies of the MLPH gene will have a blue, charcoal, Isabella (lilac) or fawn coat color depending on the other coat color genes present in the individual. In some breeds dilute coat color can be associated with...

This DNA-profile identity contains additional markers for increased reliability in parentage testing and especially for determining genetic diversity.
IT IS NOT REQUIRED IN THIS FORM BY ANY BREEDING COMPANY - the basic ISAG marker set is sufficient (article GDI100)

With this ID-profile a requirement for breeding approval at various breeding clubs in Germany but also abroad is fulfilled (see DNA-programs, e.g. DTK, DNK, DRC, VND or KZG). The set is internationally distributed and consists of the 22 recommended markers.
The result is issued as an ATC certificate identity with electronic signature and can be securely communicated over the...

Application: - identification of heterozygous carriers
Genetic testing of the MC1R mutation c.916 C>T will determine whether a dog is a carrier of the predisposition for coat color 'yellow' / 'red'. The trait is inherited in an autosomal recessive manner, two copies of the e allele (genotype e/e) are required to have the characteristic yellow/red coat color.

Application:
- Identification of heterozygous carriers in breeding selection.
This test detects the mutation in the PKP1 gene which is responsible for Ectodermal dysplasia / Skin Fragility Syndrome in Chesapeake Bay Retrievers. 'ED' is an autosomal recessive skin disease in which affected puppies have extremely thin and fragile skin that peels off even when touched lightly....

PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
Application of the test:
- Identification of heterozygous, healthy carriers for breeding selection.
- Differential diagnosis of weakness of the backhand
The test determines whether the mutation in the DNM1 gene is present, which has been described as a risk factor for the occurrence of 'Exercise Induced...

Application of the test:
(a) identification of carrier animals from a mating of carrier x free animal. b) Differential diagnosis in urinary stones and inflammation of the urogenital tract.
It is investigated whether the dog carries the mutation in the gene SLC2A9, which has been described as a cause of hyperuricosuria. Hyperuricosuria is the presence of excessive amounts of...

Application.:
- Identification of carriers for long hair in short-haired dogs. - Proof of long-hair predisposition in cases of unclear phenotype.
Long hair is inherited in an autosomal recessive fashion, meaning that two copies (status L/L) of the long hair variant are required to produce long hair. Dogs with one copy (K/L) or no copies (K/K) will have short hair.

Application: - Identification of carriers. This test examines whether the dog carries the mutation in the RYR1 gene that has been found to cause malignant hyperthermia (MH). In this disease, problems with the metabolism in the skeletal muscles occur after the administration of certain anaesthetics. This can lead to hyperthermia, heart palpitations, muscle paralysis or organ...

PLEASE NOTE: the mandatory material is a min. of 2 ml EDTA-blood
Application of the test:
- Differential diagnosis in clinical PRA
- Detection of mixed-breed, healthy carriers for breeding selection
The tested mutation is a hereditary cause for the onset of PRA, especially in Labrador Retrievers.
The inheritance is autosomal recessive; the hereditary disease occurs when both...