Frame Overo

Frame Overo is a white spotting pattern most common in Quarter Horses, Paint Horses, and specific American Saddlebred and Throroughbred and Warmblood lines. Frame has a great phenotypic variablity; horses with the frame mutation may show the “typical” pattern, or no white at all. For this reason, all horses that may carry frame should be tested before breeding, even if they do not show a white pattern. Horses with two copies of this variant are affected by Overo Lethal White Syndrome (OLWS) and die within few days after birth.